Exposes students to the current understanding of microbial pathogenesis in humans. Topics focus on how pathogens modify, disrupt, and utilize host physiologic and cellular functions for their own purposes. The significance of these interactions in terms of better understanding both pathogenesis and host biology are discussed. Additionally, the course emphasizes critical evaluation of primary literature to assist in developing novel hypotheses and designing experiments that answer critical questions in the field of microbial pathogenesis research.