Mar 28, 2024  
2022-2023 Graduate Catalog 
    
2022-2023 Graduate Catalog [ARCHIVED CATALOG]

Biomedical Sciences, Ph.D. (Cellular, Molecular and Chemical Biology Concentration)


General Program Information


Eric Beaumont, Ph.D., Associate Dean for Research and Graduate Education, Quillen College of Medicine 
B040 Stanton-Gerber Hall
Box 70407
(423) 439-2454
e-mail: beaumont@etsu.edu

Lana Cook, Ph.D., Coordinator
B040 Stanton-Gerber Hall
Box 70407
(423) 439-2031
e-mail: cookla1@etsu.edu

Biomedical Science Graduate Committee - The committee makes recommendations concerning the academic program, curriculum, recruitment, student advisement, and financial assistance and advises the Recruitment and Admissions subcommittee for the Ph.D. program.

Member   Affiliation
Dr. Russell Brown brown1@etsu.edu Neuroscience (Committee Chair)
Dr. Lana Cook cookla1@etsu.edu Biomedical Science Graduate Program (ex officio)
Dr. Chad Frasier frasierc@etsu.edu Cardiovascular Sciences
Dr. Dhirendra Kumar kumard@etsu.edu Cellular, Molecular, and Chemical Biology
Dr. Jonathan Moorman moorman@etsu.edu Immunology, Inflammation, and Infectious Diseases
Mr. Craig Land landca@etsu.edu Graduate Student Representative
Dr. Eric Beaumont beaumont@etsu.edu  Associate Dean for Research & Graduate Education, (ex officio)
Dr. Ashana Puri puria1@etsu.edu Pharmaceutical Sciences

The Biomedical Science Program of the James H. Quillen College of Medicine offers courses of study leading to the Doctor of Philosophy in Biomedical Science with concentrations in cardiovascular sciences; cellular, molecular and chemical biology; immunology, inflammation and infectious diseases; neuroscience and pharmaceutical sciences. The program is designed to prepare students for professional careers in research in the life sciences. Graduates find career opportunities in a variety of settings including universities, health science centers, health care industry, pharmaceutical and biotechnology companies.

Doctor of Philosophy Degree Requirements


A unique feature of the Ph.D. program is its multidisciplinary character, giving students a broad choice of faculty and laboratories for their research training. Students are admitted centrally rather than to departmental graduate programs and need not select an area of concentration until the end of the first year of study. An interdisciplinary core curriculum covers the basic knowledge and skills necessary for research in all areas of the biomedical sciences. Students may also become familiar with the laboratory environment of different faculty by participating in laboratory rotations. After choosing a research advisor, students receive individualized research training. There are currently over 70 faculty from eight departments participating in the graduate program.

Admission Requirements - In addition to the Graduate School admissions requirements, a curriculum vitae and three letters of recommendation are required. During the review process, a personal interview may be required. All applications for admission to the Ph.D. program will be reviewed by the Recruitment and Admissions Subcommittee of the Biomedical Science Program. Admission decisions are made on the basis of an overall evaluation of the applicant’s ability to complete advanced study in Biomedical Science. In the review of applications, particular attention is also paid to the applicant’s cumulative GPA and performance in physical science and natural sciences courses. 

Program of Study - The course of study leading to the Ph.D. degree in biomedical sciences will be designed in accord with the student’s prior training, the student’s stated interests and goals, and the specific background required for demonstration of competence in an area of biomedical science. A minimum of 60 credit-hours are required beyond the baccalaureate degree. Students accepted into the Ph.D. program in Biomedical Sciences who have earned an M.S. Biology degree from East Tennessee State University may have a program of study that is up to 16 credit hours shorter depending on coursework taken as part of the M.S. Biology program. For admission to candidacy, at least 30 of the minimum 60 credit-hours must be earned in courses at the 6000 and 7000 level. More than the minimum hours may be needed for completion of the degree program.

Note of Course Starting Dates - Some graduate courses in biomedical science are taught in conjunction with the James H. Quillen College of Medicine, and course starting dates coincide with those of the College of Medicine, usually at least two weeks prior to other graduate courses.

Non-degree students - Non-degree students may register for graduate courses in the biomedical science program with permission of the course director and Associate Dean for Research and Graduate Education. Graduate courses that are taught in conjunction with the James H. Quillen College of Medicine are not open to non-degree students. Any exception must be approved by the Dean of the College of Medicine.

Course Requirements - The core curriculum is designed to provide a broad multidisciplinary background for all students in the Biomedical Science graduate program.

Biomedical Sciences, Ph.D. Degree Requirements: 60-72 credits


Core Requirements 22 credits
Concentration 18 credits
     Required Courses    (12 credits)
     Focused Courses    (6 credits)
Seminar 4 credits
Dissertation Research 16-28 credits
TOTAL 60-72 credits

Cellular, Molecular and Chemical Biology Concentration: 18 credits


Seminar: 4 credits


Dissertation Research: 16-28 credits


Additional Information


Advisory Committee - An academic advisor will be appointed at the time of admission by the Associate Dean for Research and Graduate Education and will assist the student in planning the program of study through the first year. Each student will select a research advisor following completion of the first year in the program. The research advisor will assume primary responsibility for the student’s academic and research progress. Prior to the beginning of the second year of study, students will form a graduate advisory committee. The advisory committee will be comprised of three faculty members from the student’s primary research concentration, one faculty member from outside the student’s/advisor’s primary concentration and one faculty member outside the student’s/advisor’s department. This faculty member may or may not be in the same primary research concentration. There would be a minimum of five faculty members on the committee (with the faculty advisor as chair of the committee). The student’s research advisor will serve as chair of the committee and must hold full or associate graduate faculty status. Other members of the committee will be selected by the student and research advisor and will be approved by the departmental chair and Associate Dean for Research and Graduate Education. The committee will be responsible for overseeing the student’s overall academic program, including the program of study, preliminary examination, advancement to candidacy and preparation and defense of the dissertation. The advisory committee should meet formally with the student at least once each year to review the research and academic progress.

The Preliminary Examination - A preliminary examination may be administered at the discretion of the advisory committee after one semester of enrollment. The examination will be designed to evaluate the student’s potential to complete a total planned program and to aid in planning the program of study.

Change in Program of Study - Changes in the planned program of study for candidacy must be approved by the Dean of the College of Graduate and Continuing Studies. Forms for program changes are available on the Graduate School website.

Residence Requirements - A period of one academic year (two continuous semesters) will be required in keeping with the needs of the program and with accreditation standards. A student may be assigned to study at an off-campus site for special programs. This study must be approved in advance by the student’s graduate advisory committee to be applied toward residency requirements. No more than nine credit-hours of credit may be earned in special programs.

Time Limits - Credit received more than seven years prior to the awarding of the degree will not be accepted as part of the degree requirements.

Qualifying Examination - The qualifying examination will be administered by the advisory committee. The qualifying exam should be completed no later than three months after completion of the core curriculum. If the qualifying exam is not attempted or passed by this deadline, a period of remediation will be extended until the end of the third year.  Students must petition the Associate Dean for Research and Graduate Education for exemptions or extensions of this deadline. Successful completion of the examination should demonstrate that the student has obtained a breadth of knowledge in biomedical science, utilizing the information obtained in the core curriculum. The student should also demonstrate competence in researching the literature and organizing and presenting information on a topic of current importance. The format of the written examination will be a research proposal similar in style to a research grant application. The topic can be selected either by the student and approved in advance by the committee or by the advisory committee.  An oral examination, in which the student defends the written research, follows successful completion of the written requirement.

The Final Examination - The final examination will be oral and will be devoted to an evaluation and defense of the student’s dissertation. A student must be a formally admitted candidate for the doctorate for one full semester before being eligible to take the final examination. Students will not be allowed to complete a program during the same semester in which they are formally admitted to doctoral candidacy. The examination for defense of the dissertation will not be scheduled until the student’s dissertation is accepted by the graduate advisory committee. However, this approval and the final oral examination must both take place by the deadline in the university calendar. Each doctoral student’s final oral examination will be publicly announced. It will be an open examination, and all interested persons will be encouraged to attend.

Graduate Faculty Representation at Dissertation Defenses - The defense of the dissertation is a formal gathering at which the doctoral candidate presents and defends her or his research to members of the university community. The defense is a capstone event in the development of graduate students as scholars, professionals, or future teachers and must entail open and fair exchange of scholarly views. A member of the graduate faculty from outside the candidate’s committee and department must be present at the defense to monitor the process. The procedure to be followed in scheduling an oral defense and the format for the graduate faculty representative’s narrative report are available on the Graduate School website.

Dissertation - All doctoral candidates must complete a dissertation as a major requirement for the Ph.D. degree. The dissertation topic will be selected by the candidate with the advice and approval of the graduate advisory committee. The student must present a prospectus describing the research project for review and approval by the graduate advisory committee. After the dissertation topic has been researched, written, and accepted by the committee, it must be prepared in the proper format and submitted to the Graduate School by the initial submission deadline listed in the Academic Calendar. The Graduate School receives the submission electronically. Please follow the guidelines and checklist of requirements listed on the Electronic Thesis and Dissertations (ETD) website for further instructions.

Institutional Review Board - Student research involving human subjects must be approved by the East Tennessee State University Institutional Review Board prior to initiation of the research. This is necessary to protect the rights of human subjects involved in physical, psychological, or social research. Following approval of the proposed research by the review board, the subject involved must be informed of the study and consent to participate. The application forms for research involving human subjects and review of such research projects are available in the Office of Research and Sponsored Programs, 1110 Seminole Drive.

Evaluation - The evaluation of an advanced graduate student is a function of the instructors and the student’s graduate advisory committee. The latter has full authority for program planning and the evaluation of oral and written preliminary and qualifying examinations, provided that all university and departmental requirements have been met.